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Interchemie Werken 'De Adelaar' Bv
Horsterweg 26A, 5811 AC, Castenray
Netherlands (Holland)
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Biogenta

 Active Pharmaceutical Ingredients
Composition:
Contains per ml:
150 mg. Amoxycillin trihydrate
40 mg. Gentamycin base
1 ml. Solvents ad



Description:
The combination of amoxicillin and gentamicin acts synergistically against a wide range of infections caused by both Gram-positive (e.g. Staphylococcus, Streptococcus and Corynebacterium spp.) and Gram-negative (e.g. E.coli, Pasteurella, Salmonella and Pseudomonas spp.) bacteria in cattle and swine. Amoxicillin inhibits mainly in Gram-positive bacteria the cross-linkage between the linear peptidoglycan polymer chains that make up a major component of the cell wall. Gentamicin binds to the 30S subunit of the ribosome of mainly Gram-negative bacteria, thereby interrupting protein synthesis. Excretion of Biogenta occurs mainly unchanged via urine, and to a lesser degree via milk.

Indications:
Cattle: gastrointestinal, respiratory and intramammary infections caused by bacteria sensitive to the combination of amoxicillin and gentamicin, such as pneumonia, diarrhoea, bacterial enteritis, mastitis, metritis and cutaneous abscesses.
Swine: respiratory and gastrointestinal infections caused by bacteria sensitive to the combination of amoxicillin and gentamicin, such as pneumonia, colibacillosis, diarrhoea, bacterial enteritis and mastitis-metritis-agalactia syndrome (MMA).



Contra indications:
Hypersensitivity towards amoxicillin or gentamicin.
Administration to animals with a seriously impaired liver and/or renal function.
Concurrent administration of tetracyclines, chloramphenicol, macrolides and lincosamides.
Concurrent administration of nephrotoxic compounds.


Side effects:
Hypersensitivity reactions.

Dosage:
For intramuscular administration. The general dosage is 1 ml per 10 kg body weight per day for 3 days.

Cattle: 30-40 ml per animal per day for 3 days.
Calves: 10-15 ml per animal per day for 3 days.
Swine: 5-10 ml per animal per day for 3 days.
Piglets: 1-5 ml per animal per day for 3 days.

Shake well before use. Do not administer more than 20 ml in cattle or more than 10 ml in swine per injection site to favour absorption and dispersion.


Withdrawal times:
- For meat: 30 days.
- For milk: 2 days.


Packing:
Vial of 100 ml.

General product information:



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