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Interchemie Werken 'De Adelaar' Bv
Horsterweg 26A, 5811 AC, Castenray
Netherlands (Holland)
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Colexin Ws

 Active Pharmaceutical Ingredients
Composition:
Contains per gram powder:
1 200 000 IU. Colistin sulphate
200 mg. Trimethoprim
1 g. Carrier ad.


Description:
The combination of colistin and trimethoprim acts additive. Colistin is an antibiotic from the group of polymyxins with a bactericidal action against Gram-negative bacteria like E. coli, Haemophilus and Salmonella. Since colistin is absorbed for a very small part after oral administration only gastrointestinal indications are relevant. Trimethoprim is an antibacterial agent with a bacteriostatic action against many Gram-negative and Gram-positive bacteria like E. coli, Haemophilus, Pasteurella, Salmonella, Staphylococcus and Streptococcus spp. After oral administration trimethoprim is absorbed almost totally and penetrates well into tissues and cells.

Indications:
Gastrointestinal infections caused by colistin and trimethoprim sensitive micro-organisms, like E. coli, Haemophilus, Pasteurella, Salmonella, Staphylococcus and Streptococcus spp., in calves, goats, poultry, sheep and swine.

Contra indications:
Hypersensitivity to trimethoprim and/or colistin.
Administration to animals with a serious impaired renal function.
Administration to animals with an active microbiological digestion.


Side effects:
Renal dysfunction, neurotoxicity and neuromuscular blockade.

Dosage:
For oral administration:

Calves, goats and sheep: Twice daily 5 gram per 100 kg. body
weight for 3 - 5 days.
Poultry and swine : 1 kg. per 1000 - 2000 litre drinking
water for 3 - 5 days.

Note: for pre-ruminant calves, lambs and kids only.

Please note: Before adding to the drinking water make a presolution of 1 kg. Colexin WS per 40 litres water with a temperature of 40 degrees Celsius.

Withdrawal times:
- For meat: 7 days.

Packing:
Sachet of 100 gram and jar of 500 & 1000 gram.

General product information:



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