Colexin Ws
Komposition
Contains per gram powder:1 200 000 IU. Colistin sulphate
200 mg. Trimethoprim
1 g. Carrier ad.
Verschreibung
The combination of colistin and trimethoprim acts additive. Colistin is an antibiotic from the group of polymyxins with a bactericidal action against Gram-negative bacteria like E. coli, Haemophilus and Salmonella. Since colistin is absorbed for a very small part after oral administration only gastrointestinal indications are relevant. Trimethoprim is an antibacterial agent with a bacteriostatic action against many Gram-negative and Gram-positive bacteria like E. coli, Haemophilus, Pasteurella, Salmonella, Staphylococcus and Streptococcus spp. After oral administration trimethoprim is absorbed almost totally and penetrates well into tissues and cells.Indikation
Gastrointestinal infections caused by colistin and trimethoprim sensitive micro-organisms, like E. coli, Haemophilus, Pasteurella, Salmonella, Staphylococcus and Streptococcus spp., in calves, goats, poultry, sheep and swine.Kontra-Indikationen
Hypersensitivity to trimethoprim and/or colistin.Administration to animals with a serious impaired renal function.
Administration to animals with an active microbiological digestion.
Nebenwirkungen
Renal dysfunction, neurotoxicity and neuromuscular blockade.Dosierung
For oral administration:Calves, goats and sheep: Twice daily 5 gram per 100 kg. body
weight for 3 - 5 days.
Poultry and swine : 1 kg. per 1000 - 2000 litre drinking
water for 3 - 5 days.
Note: for pre-ruminant calves, lambs and kids only.
Please note: Before adding to the drinking water make a presolution of 1 kg. Colexin WS per 40 litres water with a temperature of 40 degrees Celsius.