Dimoxan Ws
Komposition
Contains per gram powder:1 200 000 IU. Colistin sulphate
200 mg. Amoxycillin trihydrate
1 g. Carrier ad.
Verschreibung
The combination of amoxycillin and colistin acts additive. Amoxycillin is a semisynthetic broad-spectrum penicillin with a bactericidal action against both Gram-positive and Gram-negative bacteria. The range of effect includes Campylobacter, Clostridium, Corynebacterium, E. coli, Erysipelothrix, Haemophilus, Pasteurella, Salmonella, penicillinase negative Staphylococcus and Streptococcus, spp. The bactericidal action is due to inhibition of cell wall synthesis. Amoxycillin is mainly excreted in urine. A major part can also be excreted in bile. Colistin is an antibiotic from the group of polymyxins with a bactericidal action against Gram-negative bacteria like E. coli, Haemophilus and Salmonella. Since colistin is absorbed for a very small part after oral administration only gastrointestinal indications are relevant.Indikation
Gastrointestinal, respiratory and urinary tract infections caused by amoxycillin and colistin sensitive micro-organisms, like Campylobacter, Clostridium, Corynebacterium, E. coli, Erysipelothrix, Haemophilus, Pasteurella, Salmonella, penicillinase negative Staphylococcus and Streptococcus spp., in calves, goats, poultry, sheep and swine.Kontra-Indikationen
Hypersensitivity to amoxycillin and/or colistin.Administration to animals with a serious impaired renal function.
Concurrent administration with tetracyclines, chloramphenicol, macrolides and lincosamides.
Administration to animals with an active microbiological digestion.
Nebenwirkungen
Hypersensitivity reactions, renal dysfunction, neurotoxicity and neuromuscular blockade.Dosierung
For oral administration:Calves, goats and sheep: Twice daily 5 gram per 100 kg. body
weight for 3 - 5 days.
Poultry and swine : 1 kg. per 1000 - 2000 litre drinking
water for 3 - 5 days.
Note: for pre-ruminant calves, lambs and kids only.
Please note: Before adding to the drinking water make a presolution of 1 kg. Dimoxan WS per 20 litres water with a temperature of 40 degrees Celsius.