Intertrim-500 Ws
Komposition
Contains per gram powder:400 mg. Sulfadiazine
100 mg. Trimethoprim
1 g. Carrier ad.
Verschreibung
The combination of trimethoprim and sulfadiazine acts synergistic and usually bactericidal against many Gram-positive and Gram-negative bacteria like E. coli, Haemophilus, Pasteurella, Salmonella, Staphylococcus and Streptococcus spp. Both compounds affect bacterial purine synthesis in a different way, as a result, of which a double blockade is accomplished.Indikation
Gastrointestinal and respiratory infections caused by trimethoprim and sulfadiazine sensitive micro-organisms, like E. coli, Haemophilus, Pasteurella, Salmonella, Staphylococcus and Streptococcus spp., in calves, sheep, goats, poultry and swine.Kontra-Indikationen
Hypersensitivity to trimethoprim and/or sulphonamides.Administration to animals with a serious impaired renal and/or liver function or with blood dyscrasias.
Nebenwirkungen
After long-term treatment and high dosages crystalluria can occur.When symptoms of crystalluria occur (haematuria, kidney colic), treatment has to be stopped immediately and for example sodium carbonate (alkalinises) has to be administered for increasing urine solubility of sulfadiazine. Administration for a prolonged period also increases the risk for blood dyscrasias.
Anaemia, leucopenia and thrombocytopenia.
Dosierung
For oral administration:Calves, goats and sheep: Twice daily 5 gram per 100 kg. body
weight for 4 -7 days.
Poultry and swine : 1 kg. per 1500 - 2500 litre drinking
water for 4 7 days.
Note: for pre-ruminant calves, lambs and kids only.
Rückruf-Zeiten
- For meat:Calves, sheep, goats and swine: 8 days.
Poultry: 5 days.